Although taught in school to sit at our desks and not stir, research continually shows that sitting for long periods is bad for health. Would you stand at a desk all day rather than sit in an Aeron chair though? Apparently Thomas Jefferson and Winston Churchill had them. And AJ Jacobs goes as far to work/write when on a DIY treadmill desk he rigged. If you can’t get used to the idea though, research suggests to get up and move every hour.